RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
mir-375
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
Dual-luciferase reporter assay; qRT-PCR etc.
Target
Frizzled 8
Pathway
Wnt/B-catenin signaling pathway
PubMed ID
Title
MiR-375 regulates rat alveolar epithelial cell trans-differentiation by inhibiting Wnt/B-catenin pathway
Year
2013
Function
MiR-375 was downregulated during AEC trans-differentiation; MiR-375 regulates AEC trans-differentiation through the Wnt/B-catenin pathway by targeting Frizzled 8.